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S obzirom na to da je rizik od pojave fenomena obustave/rebound fenomena veći ukoliko se terapija naglo prekine, preporučuje se postepeno smanjivanje doze.

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The risk is larger in small children who're obese or have respiratory issues, or soon after sure surgeries (which include tonsil/adenoid removing). Speak with your medical doctor or pharmacist about the hazards and advantages of this medication.

Codeine is changed to morphine in the human body. A lot of people improve codeine to morphine much more promptly than Many others. These men and women are known as "extremely-speedy metabolizers of codeine". Get hold of your medical doctor right away if you experience extreme sleepiness, confusion, or shallow respiratory.

Fenitoin je poznati induktor CYP3A4 i ubrzava metabolizam diazepama u jetri. Smanjeno dejstvo diazepama. Diazepam deluje na metabolizam fenitoina na nepredvidiv način: metabolizam fenitoina pod here dejstvom diazepama može biti ubrzan ili usporen, ili ostati nepromenjen.

4. Moguća neželjena dejstva Kao i svi lekovi, ovaj lek može da prouzrokuje neželjena dejstva, iako ona ne moraju da se jave kod svih pacijenata koji uzimaju ovaj lek.

Podeona linija služi samo da olakša lomljenje da bi se lek lakše progutao, a ne za podelu na jednake doze.

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Istovremena primena diazepama i opioida može dovesti do sedacije, respiratorne depresije, kome i smrti. Usled ovih rizika, istovremeno propisivanje sedativnih lekova poput benzodiazepina ili sličnih lekova kao što je diazepam sa opioidima treba rezervisati za pacijente kod kojih alternativne terapijske opcije nisu moguće.

Codeine sulfate tablets should not be utilised To ease pain right after surgical procedures removal of tonsils or adenoids in any kids 12 to eighteen several years of age. Severe breathing complications and deaths have already been documented in a few young children who gained codeine immediately after tonsil or adenoid surgical procedures.

This medication should not be used To ease ache after surgical procedures removal of tonsils or adenoids in any small children. Significant respiration complications and deaths are noted in certain little ones who acquired codeine following tonsil or adenoid surgical procedure.

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